A literature review describing the morphological features of normal neutrophils and their changes in various diseases is presented. Parameters of neutrophil granulocyte nuclei are described, changes in nuclei are characterized in congenital and acquired pathology. The characteristics of the cytoplasm of normal neutrophils and its changes in pathological conditions are also given. Various types of cytoplasmic inclusions present in normal cells and formed in both hereditary and acquired diseases are described in detail. The problems of clinical and diagnostic significance of changes in the morphology of neutrophils are discussed.
Dmitriy Yu. Sosnin – MD, PhD, professor at the Department of Faculty Therapy N 2, Occupational Pathology and Clinical Laboratory Diagnostics of the Wagner State Medical University, E. A. Vagner Perm State Medical University, Ministry of Health of Russian Federation, Perm, Russia. E-mail: This email address is being protected from spambots. You need JavaScript enabled to view it.
Vladimir V. Bazarnyi – MD, PhD, Prof., Professor of the Department of Clinical Laboratory Diagnostics and Bacteriology, Chief Researcher of the Department of General Pathology of the Central Scientific Research Laboratory of the Ural State Medical University; Vice-Rector for Research and Clinical Affairs, FSBEI HE “Ural State Medical University” of the Ministry of Health of the Russian Federation, Yekaterinburg, Russia. E-mail: vlad-bazarny@yandeх.ru.
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